http://littlemisshannah.com/2009/01/possible-oral-enzyme-replacement-therapy-instead-of-iv-infusion/ Our Fight against Gaucher's Disease type 2 or 3 Thu, 09 Feb 2012 17:34:53 +0000 hourly 1 http://wordpress.org/?v=3.3.1 http://littlemisshannah.com/2009/01/possible-oral-enzyme-replacement-therapy-instead-of-iv-infusion/comment-page-1/#comment-297 Maureen Fri, 30 Jan 2009 14:55:19 +0000 http://littlemisshannah.com/?p=808#comment-297 Just as a person who likes to read, examine, and critique medical studies, one thing that stood out to me was the words "increased target enzyme activity levels". If I remember correctly, Hannah's enzyme level (for at least one of the enzymes) is 0. It makes me curious if it has been shown to CREATE an enzyme level for her (since she produces none it can be an entirely different thing than a person who is producing some but not enough in other diseases; I have no idea if it is the same for Gaucher's but that thought did come to mind). I don't want to rain on your parade of hope, but it is a question I would ask if it was me. Just as a person who likes to read, examine, and critique medical studies, one thing that stood out to me was the words “increased target enzyme activity levels”. If I remember correctly, Hannah’s enzyme level (for at least one of the enzymes) is 0. It makes me curious if it has been shown to CREATE an enzyme level for her (since she produces none it can be an entirely different thing than a person who is producing some but not enough in other diseases; I have no idea if it is the same for Gaucher’s but that thought did come to mind). I don’t want to rain on your parade of hope, but it is a question I would ask if it was me.

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